The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal. [electronic resource]
Producer: 20070126Description: 660-70 p. digitalISSN:- 0946-2716
- Adenosine Triphosphate -- analogs & derivatives
- Alternative Splicing
- Amino Acid Motifs
- Amino Acid Sequence
- Cell Line
- DNA Repair Enzymes -- genetics
- Exons
- Humans
- Hydrolysis
- Isoenzymes -- genetics
- Mitochondria -- metabolism
- Molecular Sequence Data
- Phosphoric Monoester Hydrolases -- genetics
- Polymorphism, Single Nucleotide
- Protein Sorting Signals -- genetics
- Protein Transport
- Recombinant Fusion Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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