Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation. [electronic resource]
Producer: 20061030Description: 1089-95 p. digitalISSN:- 0887-6924
- Cell Transformation, Neoplastic -- genetics
- Cytidine Deaminase -- genetics
- Gene Expression Profiling
- Humans
- Immunoglobulin Heavy Chains -- genetics
- Immunoglobulin Variable Region -- genetics
- Leukemia, Lymphocytic, Chronic, B-Cell -- genetics
- Mutation
- PAX5 Transcription Factor -- genetics
- Proto-Oncogene Proteins c-myc -- genetics
- RNA, Messenger -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Somatic Hypermutation, Immunoglobulin -- genetics
- Transcription Factors -- genetics
- rho GTP-Binding Proteins -- genetics
- AICDA (Activation-Induced Cytidine Deaminase)
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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