Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. [electronic resource]
Producer: 20060626Description: 1200-9 p. digitalISSN:- 0022-3565
- Aryl Hydrocarbon Hydroxylases -- genetics
- Base Sequence
- Cell Line, Tumor
- Constitutive Androstane Receptor
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- genetics
- Electrophoretic Mobility Shift Assay
- Gene Expression Regulation, Enzymologic -- drug effects
- Genes, Reporter
- Hepatocytes -- drug effects
- Humans
- Liver -- drug effects
- Molecular Sequence Data
- Oxidoreductases, N-Demethylating -- genetics
- Oximes -- pharmacology
- Pregnane X Receptor
- Protein Binding
- Receptor Cross-Talk -- physiology
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, Steroid -- agonists
- Reverse Transcriptase Polymerase Chain Reaction
- Rifampin -- pharmacology
- Thiazoles -- pharmacology
- Transcription Factors -- agonists
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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