An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors. [electronic resource]
Producer: 20060510Description: 202-6 p. digitalISSN:- 1552-4450
- Animals
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Cell Line, Tumor
- Cells, Cultured
- DNA Damage
- Electronic Data Processing
- Fibroblasts -- metabolism
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Genetic Techniques
- Humans
- Imidazoles -- chemistry
- Intracellular Signaling Peptides and Proteins -- chemistry
- Mice
- Microscopy, Fluorescence
- Models, Chemical
- Neoplasms -- drug therapy
- Nuclear Proteins
- Nucleic Acid Hybridization
- Oligonucleotide Array Sequence Analysis
- Phosphoproteins -- chemistry
- Piperazines -- chemistry
- Plasmids -- metabolism
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- chemistry
- Signal Transduction
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor p53-Binding Protein 1
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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