RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells. [electronic resource]
Producer: 20060718Description: 440-50 p. digitalISSN:- 0730-2312
- Breast Neoplasms -- drug therapy
- Cell Death -- drug effects
- Female
- Humans
- Insulin Receptor Substrate Proteins
- Phosphoproteins -- chemistry
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- RNA, Small Interfering -- genetics
- Receptors, Estrogen -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Tamoxifen -- pharmacology
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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