Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells. [electronic resource]
Producer: 20050923Description: 96-106 p. digitalISSN:- 0014-2999
- Acetylcysteine -- pharmacology
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Apoptotic Protease-Activating Factor 1
- BH3 Interacting Domain Death Agonist Protein
- Blotting, Western
- Carcinoma, Hepatocellular -- metabolism
- Carrier Proteins -- metabolism
- Caspase 3
- Caspase 8
- Caspase 9
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cysteine Proteinase Inhibitors -- pharmacology
- Cytochromes c -- metabolism
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- Flow Cytometry
- Humans
- Intracellular Membranes -- drug effects
- Intracellular Signaling Peptides and Proteins
- Isothiocyanates -- pharmacology
- Liver Neoplasms -- metabolism
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Mitochondrial Proteins -- metabolism
- Oligopeptides -- pharmacology
- Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation -- drug effects
- Vitamin E -- pharmacology
- X-Linked Inhibitor of Apoptosis Protein
- bcl-2-Associated X Protein
- fas Receptor -- metabolism
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Publication Type: Journal Article
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