Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin-epithelin precursor (GEP), a prosurvival factor for ovarian cancer. [electronic resource]
Producer: 20051115Description: 7084-93 p. digitalISSN:- 0950-9232
- Adjuvants, Immunologic -- pharmacology
- Apoptosis -- drug effects
- Blotting, Northern
- Blotting, Western
- Caspase 3
- Caspases -- metabolism
- Cell Nucleus -- drug effects
- Cell Proliferation -- drug effects
- Chelating Agents -- pharmacology
- Cholera Toxin -- pharmacology
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Egtazic Acid -- analogs & derivatives
- Endothelins -- pharmacology
- Female
- Guanine Nucleotide Exchange Factors -- metabolism
- Humans
- Intercellular Signaling Peptides and Proteins -- chemistry
- Lysophospholipids -- pharmacology
- MAP Kinase Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Ovarian Neoplasms -- metabolism
- Pertussis Toxin -- pharmacology
- Poly(ADP-ribose) Polymerases -- metabolism
- Progranulins
- Tumor Cells, Cultured
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Publication Type: Journal Article
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