Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. [electronic resource]
Producer: 20050825Description: 49-59 p. digitalISSN:- 1535-6108
- Apoptosis
- Caspase 3
- Caspases -- metabolism
- Cell Cycle Proteins -- metabolism
- Drug Resistance
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Genes, cdc -- physiology
- HeLa Cells
- Humans
- Kinesins -- antagonists & inhibitors
- Mitosis -- drug effects
- Molecular Structure
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Pyrroles -- pharmacology
- Spindle Apparatus -- physiology
- bcl-2-Associated X Protein
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Publication Type: Journal Article
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