Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains. [electronic resource]
Producer: 20051018Description: 653-65 p. digitalISSN:- 0198-8859
- Cell Line, Tumor
- Cell Membrane -- drug effects
- Cholesterol -- metabolism
- Cytoplasmic Vesicles -- drug effects
- Gene Expression -- drug effects
- HeLa Cells
- Histocompatibility Antigens Class I -- biosynthesis
- Histocompatibility Antigens Class II -- biosynthesis
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Intracellular Fluid -- drug effects
- Membrane Microdomains -- drug effects
- Promoter Regions, Genetic -- drug effects
- Protein Biosynthesis -- drug effects
- Protein Transport -- drug effects
- Simvastatin -- pharmacology
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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