A genetic screen in Caenorhabditis elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking. [electronic resource]
Producer: 20050919Description: 774-85 p. digitalISSN:- 0022-3042
- Adrenergic Agents -- pharmacology
- Animals
- Animals, Genetically Modified
- Blotting, Western -- methods
- Caenorhabditis elegans
- Cells, Cultured
- Dopamine -- metabolism
- Dopamine Plasma Membrane Transport Proteins
- Genetic Testing -- methods
- Genomics -- methods
- Green Fluorescent Proteins -- biosynthesis
- Membrane Glycoproteins -- biosynthesis
- Membrane Transport Proteins -- biosynthesis
- Models, Molecular
- Mutagenesis -- physiology
- Mutation
- Nerve Tissue Proteins -- biosynthesis
- Neurons -- classification
- Oxidopamine -- pharmacology
- Protein Transport -- genetics
- RNA, Messenger -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Transfection -- methods
- Tritium -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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