A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion. [electronic resource]
Producer: 20060214Description: 16 p. digitalISSN:- 1471-2415
- Becaplermin
- Cell Adhesion -- drug effects
- Cell Count
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival
- Cells, Cultured
- Chemotaxis -- drug effects
- Extracellular Matrix Proteins -- metabolism
- Fibroblast Growth Factor 2 -- pharmacology
- Flow Cytometry
- Gestational Age
- Humans
- Integrin alphaVbeta3 -- antagonists & inhibitors
- Integrins -- antagonists & inhibitors
- Peptides, Cyclic -- pharmacology
- Pigment Epithelium of Eye -- cytology
- Platelet-Derived Growth Factor -- pharmacology
- Proto-Oncogene Proteins c-sis
- Receptors, Vitronectin -- antagonists & inhibitors
- Serum
- Up-Regulation
- Vascular Endothelial Growth Factor A -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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