A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas. [electronic resource]
Producer: 20050929Description: 1801-7 p. digitalISSN:- 0006-4971
- Animals
- CCAAT-Enhancer-Binding Protein-beta -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Down-Regulation -- drug effects
- Everolimus
- Hodgkin Disease -- metabolism
- Humans
- Lymphoma, Large B-Cell, Diffuse -- metabolism
- Mice
- Mice, Inbred NOD
- Mice, SCID
- NF-kappa B -- drug effects
- Sirolimus -- analogs & derivatives
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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