Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation. [electronic resource]
Producer: 20050816Description: 24386-95 p. digitalISSN:- 0021-9258
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid -- pharmacology
- Adenosine Diphosphate -- chemistry
- Androstadienes -- pharmacology
- Antibodies, Monoclonal -- chemistry
- Blood Platelets -- cytology
- Blood Proteins -- chemistry
- Calcium -- metabolism
- Chromones -- pharmacology
- Cyclooxygenase Inhibitors -- pharmacology
- Cytosol -- metabolism
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Fibrinogen -- chemistry
- GTP-Binding Protein alpha Subunits, Gi-Go -- genetics
- GTP-Binding Protein alpha Subunits, Gq-G11 -- genetics
- Humans
- Morpholines -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoproteins -- chemistry
- Platelet Activation
- Platelet Aggregation
- Platelet Glycoprotein GPIIb-IIIa Complex -- metabolism
- Protein Binding
- Proto-Oncogene Proteins -- metabolism
- Receptors, Cytokine -- metabolism
- Receptors, Purinergic P2 -- metabolism
- Receptors, Purinergic P2Y1
- Receptors, Thrombopoietin
- Thrombopoietin -- chemistry
- Thromboxane A2 -- metabolism
- Thromboxanes -- chemistry
- Time Factors
- Type C Phospholipases -- metabolism
- Wortmannin
- rap GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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