Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. [electronic resource]
Producer: 20050802Description: 22212-21 p. digitalISSN:- 0021-9258
- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Transporters -- metabolism
- Animals
- Apolipoprotein A-I -- metabolism
- Atorvastatin
- Cell Line
- Cholesterol -- metabolism
- Diterpenes -- pharmacology
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Gene Expression
- Gene Expression Regulation
- Genes, Dominant
- Heptanoic Acids -- pharmacology
- Humans
- Hydroxymethylglutaryl CoA Reductases -- metabolism
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Lipid Metabolism
- Lipoproteins -- metabolism
- Macrophages -- metabolism
- Mevalonic Acid -- pharmacology
- Mice
- Models, Biological
- PPAR gamma -- metabolism
- Phosphorylation
- Polyisoprenyl Phosphates -- pharmacology
- Pyrroles -- pharmacology
- RNA, Messenger -- metabolism
- Sesquiterpenes
- Transfection
- Up-Regulation
- rhoA GTP-Binding Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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