Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2. [electronic resource]
Producer: 20050607Description: 14597-604 p. digitalISSN:- 0021-9258
- Animals
- Blotting, Western
- CHO Cells
- Cell Line, Tumor
- Cricetinae
- DNA Mutational Analysis
- Dose-Response Relationship, Radiation
- ErbB Receptors -- chemistry
- Humans
- Immunoprecipitation
- Intracellular Signaling Peptides and Proteins
- Kinetics
- Ligands
- Mutation
- Phospholipase C gamma
- Phosphorylation
- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatases -- chemistry
- Radiation, Ionizing
- Signal Transduction
- Time Factors
- Transfection
- Type C Phospholipases -- metabolism
- Tyrosine -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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