Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. [electronic resource]
Producer: 20050314Description: 743-8 p. digitalISSN:- 0008-5472
- Adaptor Proteins, Signal Transducing
- Apoptosis -- drug effects
- Cell Growth Processes -- genetics
- Cell Line, Tumor
- Cytoskeletal Proteins -- deficiency
- DNA Methylation
- Dishevelled Proteins
- Down-Regulation
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Humans
- Intercellular Signaling Peptides and Proteins -- physiology
- Mesothelioma -- genetics
- Phosphoproteins -- biosynthesis
- Promoter Regions, Genetic
- Proto-Oncogene Proteins -- antagonists & inhibitors
- RNA, Small Interfering -- genetics
- Trans-Activators -- deficiency
- Transfection
- Wnt Proteins
- beta Catenin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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