DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA. [electronic resource]
Producer: 20050418Description: 779-89 p. digitalISSN:- 0261-4189
- Active Transport, Cell Nucleus -- drug effects
- Animals
- Bone Marrow -- drug effects
- Cells, Cultured
- DNA-Activated Protein Kinase
- DNA-Binding Proteins -- metabolism
- Enzyme Activation
- Macrophages -- drug effects
- Mice
- Mice, Knockout
- Oligodeoxyribonucleotides -- pharmacology
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Receptors, Cell Surface -- metabolism
- Toll-Like Receptor 9
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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