The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators. [electronic resource]
Producer: 20050624Description: 585-96 p. digitalISSN:- 0022-3042
- Animals
- Apoptosis -- drug effects
- Basic Helix-Loop-Helix Transcription Factors
- Cell Cycle Proteins -- metabolism
- Cell Survival -- drug effects
- Clone Cells
- Culture Media, Serum-Free -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cytoprotection -- physiology
- Helix-Loop-Helix Motifs -- physiology
- Nerve Tissue Proteins -- genetics
- Neurons -- cytology
- PC12 Cells
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Rats
- Transcription Factors -- genetics
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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