NPM/ALK downregulates p27Kip1 in a PI-3K-dependent manner. [electronic resource]
Producer: 20050203Description: 1265-71 p. digitalISSN:- 0301-472X
- B-Lymphocytes -- cytology
- Blotting, Western
- Carrier Proteins -- metabolism
- Cell Line, Transformed
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- genetics
- Chromones -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p27
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Leukemic -- drug effects
- Hematopoietic Stem Cells -- metabolism
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Lymphoma, Large B-Cell, Diffuse -- genetics
- Morpholines -- pharmacology
- Oligopeptides -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation -- drug effects
- Proteasome Endopeptidase Complex -- metabolism
- Protein Transport -- drug effects
- Protein-Tyrosine Kinases -- genetics
- S Phase -- drug effects
- Signal Transduction -- drug effects
- Transformation, Genetic
- Translocation, Genetic -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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