In malignant myeloid cells expression of Daxx downregulates expression of p53 and of the inhibitors of apoptosis proteins. [electronic resource]
Producer: 20050411Description: 513-8 p. digitalISSN:- 1466-4860
- Adaptor Proteins, Signal Transducing
- Carrier Proteins -- genetics
- Caspase 10
- Caspase 7
- Caspase 8
- Caspases -- drug effects
- Cell Line, Tumor
- Cell Proliferation
- Co-Repressor Proteins
- Culture Media, Serum-Free -- pharmacology
- Down-Regulation -- drug effects
- Enzyme Precursors -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Genetic Vectors -- genetics
- Humans
- Inhibitor of Apoptosis Proteins
- Intracellular Signaling Peptides and Proteins -- genetics
- Leukemia, Erythroblastic, Acute -- genetics
- Molecular Chaperones
- Nuclear Proteins -- genetics
- Promoter Regions, Genetic -- genetics
- Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- drug effects
- Transfection
- Tumor Suppressor Protein p53 -- genetics
- bcl-2-Associated X Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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