Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen. [electronic resource]
Producer: 20050118Description: 4542-9 p. digitalISSN:- 0066-4804
- Animals
- Antiviral Agents -- administration & dosage
- Cell Line
- Chromatography, Gel
- Cytopathogenic Effect, Viral -- drug effects
- Dogs
- Enzyme Inhibitors -- administration & dosage
- Guanidines
- Indicators and Reagents
- Kinetics
- Lung -- metabolism
- Male
- Mice
- Microscopy, Electron
- Neuraminidase -- antagonists & inhibitors
- Orthomyxoviridae -- drug effects
- Orthomyxoviridae Infections -- prevention & control
- Pyrans
- Rats
- Rats, Sprague-Dawley
- Sialic Acids -- chemistry
- Structure-Activity Relationship
- Viral Plaque Assay
- Virus Replication -- drug effects
- Zanamivir
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Publication Type: Journal Article
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