Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205. [electronic resource]
Producer: 20050426Description: 253-62 p. digitalISSN:- 0898-6568
- Acetamides -- pharmacology
- Acetophenones -- pharmacology
- Alkaloids
- Amino Acid Chloromethyl Ketones -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Benzophenanthridines
- Benzopyrans -- pharmacology
- Calpain -- antagonists & inhibitors
- Caspase 3
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colonic Neoplasms -- chemistry
- Cysteine Proteinase Inhibitors -- pharmacology
- DNA Fragmentation -- drug effects
- Dipeptides -- pharmacology
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Flow Cytometry
- Histones -- metabolism
- Humans
- Indomethacin -- pharmacology
- Kinetics
- Phenanthridines -- pharmacology
- Phosphorylation -- drug effects
- Protein Kinase C -- metabolism
- Protein Kinase C-delta
- Pyrans -- pharmacology
- Spiro Compounds -- pharmacology
- Tetradecanoylphorbol Acetate -- pharmacology
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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