Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion. [electronic resource]
Producer: 20050204Description: 53683-90 p. digitalISSN:- 0021-9258
- Blotting, Western
- Calpain -- metabolism
- Carcinogens
- Cell Line, Tumor
- Cell Movement
- Disease Progression
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Flavonoids -- pharmacology
- Gene Silencing
- Genetic Vectors
- Humans
- Immunoprecipitation
- Lung Neoplasms -- pathology
- Microscopy, Fluorescence
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Models, Biological
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Nitrosamines
- Phosphorylation
- RNA Interference
- RNA, Small Interfering -- metabolism
- Signal Transduction
- Tobacco Products
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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