Chimeric RNA/ethylene-bridged nucleic acids promote dystrophin expression in myocytes of duchenne muscular dystrophy by inducing skipping of the nonsense mutation-encoding exon. [electronic resource]
Producer: 20050225Description: 749-57 p. digitalISSN:- 1043-0342
- Base Sequence
- Blotting, Western
- Codon, Nonsense -- genetics
- DNA Primers
- Dystrophin -- genetics
- Ethylenes -- chemistry
- Exons -- genetics
- Genetic Therapy -- methods
- Humans
- Immunohistochemistry
- Muscle Fibers, Skeletal -- metabolism
- Muscular Dystrophy, Duchenne -- metabolism
- Oligonucleotides, Antisense -- genetics
- RNA -- chemistry
- RNA Editing -- genetics
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription, Genetic -- drug effects
- Transfection
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Publication Type: Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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