Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it. [electronic resource]
Producer: 20041109Description: 1867-77 p. digitalISSN:- 0143-3334
- Antigens, Nuclear -- metabolism
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Inducing Factor
- Caspase Inhibitors
- Caspases -- metabolism
- Colonic Neoplasms -- metabolism
- Complement Membrane Attack Complex
- Complement System Proteins
- Curcumin -- pharmacology
- Cytochromes c -- metabolism
- DNA Repair
- DNA-Binding Proteins -- antagonists & inhibitors
- Down-Regulation
- Enzyme Activation -- drug effects
- Flavoproteins -- metabolism
- Gene Expression Regulation, Neoplastic
- Glycoproteins -- metabolism
- Green Fluorescent Proteins
- Humans
- Ku Autoantigen
- Luminescent Proteins -- metabolism
- Membrane Proteins -- metabolism
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Tumor Cells, Cultured
- bcl-2-Associated X Protein
- bcl-X Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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