The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements. [electronic resource]
Producer: 20040806Description: 4122-30 p. digitalISSN:- 0008-5472
- Animals
- Apoptosis -- genetics
- Breast Neoplasms -- genetics
- Cell Line, Tumor
- Cyclin D1 -- biosynthesis
- Cyclin-Dependent Kinase Inhibitor p16 -- biosynthesis
- DNA, Neoplasm -- antagonists & inhibitors
- Fibroblasts -- metabolism
- Humans
- Mice
- Mice, Knockout
- Promoter Regions, Genetic
- Repressor Proteins -- biosynthesis
- Transcription, Genetic
- Transfection
- Tumor Suppressor Protein p14ARF -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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