Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines. [electronic resource]
Producer: 20040311Description: 3662-70 p. digitalISSN:- 0021-9258
- Basic Helix-Loop-Helix Transcription Factors
- Blotting, Western
- Bone Neoplasms -- metabolism
- Calcium -- metabolism
- Carbamates -- pharmacology
- Cell Differentiation
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Core Binding Factor Alpha 1 Subunit
- DNA -- metabolism
- Dipeptides -- pharmacology
- Enzyme Activation
- Homeodomain Proteins -- metabolism
- Humans
- Immunohistochemistry
- Intracellular Signaling Peptides and Proteins
- Male
- Membrane Proteins -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- Models, Biological
- Neoplasm Metastasis
- Neoplasm Proteins -- biosynthesis
- Osteoblasts -- metabolism
- Prostatic Neoplasms -- enzymology
- Protein Binding
- RNA -- chemistry
- RNA, Ribosomal, 18S -- chemistry
- Receptors, Notch
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Time Factors
- Transcription Factor HES-1
- Transcription Factors -- biosynthesis
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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