Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5' termini. [electronic resource]
Producer: 19920922Description: 3271-8 p. digitalISSN:- 0261-4189
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Codon
- Erythroid Precursor Cells -- metabolism
- Exons
- Exonucleases -- pharmacology
- Globins -- genetics
- Humans
- Methylation
- Methyltransferases
- Mice
- Molecular Sequence Data
- Pyrophosphatases -- pharmacology
- RNA Caps -- isolation & purification
- RNA Processing, Post-Transcriptional
- RNA, Messenger -- drug effects
- Spleen -- metabolism
- Thalassemia -- genetics
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Publication Type: Journal Article
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