HIV envelope gp120-mediated regulation of osteoclastogenesis via receptor activator of nuclear factor kappa B ligand (RANKL) secretion and its modulation by certain HIV protease inhibitors through interferon-gamma/RANKL cross-talk. [electronic resource]
Producer: 20040112Description: 48251-8 p. digitalISSN:- 0021-9258
- Animals
- Bone Diseases, Metabolic -- metabolism
- Bone Resorption
- CD3 Complex -- biosynthesis
- Carrier Proteins -- metabolism
- Cell Line
- Cells, Cultured
- Cysteine Endopeptidases -- metabolism
- Cytokines -- metabolism
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- HIV Envelope Protein gp120 -- metabolism
- HIV Protease Inhibitors -- pharmacology
- Humans
- Immunoblotting
- Indinavir -- pharmacology
- Interferon-gamma -- metabolism
- Membrane Glycoproteins -- metabolism
- Mice
- Multienzyme Complexes -- metabolism
- Nelfinavir -- pharmacology
- Osteoclasts -- metabolism
- Precipitin Tests
- Protease Inhibitors -- pharmacology
- Proteasome Endopeptidase Complex
- Protein Binding
- RANK Ligand
- Receptor Activator of Nuclear Factor-kappa B
- Ritonavir -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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