Iron tetrakis (N-methyl-4'-pyridyl) porphyrinato inhibits proliferative activity of thymocytes by blocking activation of p38 mitogen-activated protein kinase, nuclear factor-kappaB, and interleukin-2 secretion. [electronic resource]
Producer: 20030930Description: 147-55 p. digitalISSN:- 0041-008X
- Animals
- Cell Division -- drug effects
- Cell Line
- Cell Survival -- drug effects
- Concanavalin A -- pharmacology
- Dose-Response Relationship, Drug
- Down-Regulation
- Enzyme Activation -- drug effects
- Ferric Compounds -- pharmacology
- In Vitro Techniques
- Interleukin-2 -- metabolism
- Male
- Metalloporphyrins -- pharmacology
- Mice
- Mice, Inbred Strains
- Mitogen-Activated Protein Kinases -- biosynthesis
- NF-kappa B -- biosynthesis
- Thymus Gland -- cytology
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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