An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. [electronic resource]
Producer: 20031003Description: 9506-11 p. digitalISSN:- 0027-8424
- 3T3 Cells
- Acetylation
- Animals
- Benzamides
- Blotting, Southern
- Bone Marrow Transplantation
- Core Binding Factor Alpha 2 Subunit
- DNA -- metabolism
- Flow Cytometry
- Histone Deacetylases -- metabolism
- Histones -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Imatinib Mesylate
- Leukemia, Myeloid, Acute -- etiology
- Mice
- Mice, Inbred BALB C
- Mice, Transgenic
- Models, Genetic
- Mutation
- Oncogene Proteins, Fusion -- metabolism
- Phenotype
- Piperazines -- pharmacology
- Plasmids -- metabolism
- Protein Binding
- Protein Structure, Tertiary
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins c-kit -- biosynthesis
- Pyrimidines -- pharmacology
- RUNX1 Translocation Partner 1 Protein
- Retroviridae -- genetics
- Time Factors
- Transcription Factors -- metabolism
- Vorinostat
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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