Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis. [electronic resource]
Producer: 20030411Description: 363-9 p. digitalISSN:- 0017-5749
- Adenoviridae -- genetics
- Administration, Rectal
- Animals
- Antibodies, Viral -- biosynthesis
- Cells, Cultured
- Crohn Disease -- immunology
- Epithelial Cells -- immunology
- Gene Transfer Techniques
- Genetic Therapy -- methods
- Genetic Vectors -- administration & dosage
- Humans
- Interleukin-10 -- biosynthesis
- Intestinal Mucosa -- immunology
- Lipopolysaccharides -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Spleen -- immunology
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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