Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia. [electronic resource]
Producer: 20030408Description: 425-32 p. digitalISSN:- 0006-4971
- Acute Disease
- Adolescent
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Cytarabine -- administration & dosage
- Down-Regulation -- drug effects
- Female
- Genes, bcl-2 -- drug effects
- Granulocyte Colony-Stimulating Factor -- administration & dosage
- Humans
- Leukemia -- complications
- Male
- Middle Aged
- Oligonucleotides, Antisense -- administration & dosage
- Remission Induction -- methods
- Salvage Therapy
- Thionucleotides -- administration & dosage
- Vidarabine -- administration & dosage
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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