Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy. [electronic resource]
Producer: 20020701Description: 7640-5 p. digitalISSN:- 0027-8424
- Antineoplastic Agents -- therapeutic use
- Base Sequence
- Drug Resistance, Neoplasm -- genetics
- Genetic Variation
- Humans
- Introns
- Leukemia, Promyelocytic, Acute -- classification
- Molecular Sequence Data
- Neoplasm Proteins -- genetics
- Oncogene Proteins, Fusion -- genetics
- Receptors, Retinoic Acid -- genetics
- Retinoic Acid Receptor alpha
- Retinoid X Receptors
- Sequence Alignment
- Sequence Analysis, DNA
- Sequence Homology, Nucleic Acid
- Transcription Factors -- genetics
- Transcription, Genetic
- Tretinoin -- therapeutic use
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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