Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. [electronic resource]
Producer: 20020510Description: 1118-24 p. digitalISSN:- 0012-1797
- Allopurinol -- therapeutic use
- Animals
- Diabetes Mellitus, Experimental -- physiopathology
- Diabetes Mellitus, Type 1 -- drug therapy
- Double-Blind Method
- Free Radical Scavengers -- therapeutic use
- Free Radicals -- metabolism
- Glutathione -- metabolism
- Glutathione Disulfide -- metabolism
- Heart -- drug effects
- Humans
- Kinetics
- Lipid Peroxidation -- drug effects
- Liver -- drug effects
- Male
- Malondialdehyde -- metabolism
- Membrane Potentials -- drug effects
- Mitochondria, Heart -- drug effects
- Myocardium -- metabolism
- Oxidative Stress -- drug effects
- Rats
- Rats, Wistar
- Xanthine Oxidase -- antagonists & inhibitors
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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