The impact of p53 status on cellular sensitivity to antifolate drugs. [electronic resource]
Producer: 20011025Description: 2114-23 p. digitalISSN:- 1078-0432
- Apoptosis -- drug effects
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- genetics
- DNA Mutational Analysis
- DNA, Neoplasm -- chemistry
- Dose-Response Relationship, Drug
- Folic Acid Antagonists -- pharmacology
- Gene Expression Regulation, Neoplastic -- radiation effects
- Genotype
- Glutamates -- pharmacology
- Guanine -- analogs & derivatives
- Humans
- Methotrexate -- pharmacology
- Mutation
- Pemetrexed
- Quinazolines -- pharmacology
- Sensitivity and Specificity
- Tetrahydrofolates -- pharmacology
- Thiophenes -- pharmacology
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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