L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice. [electronic resource]
Producer: 20010913Description: 61-68 p. digitalISSN:- 0304-3959
- 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer -- pharmacology
- Amlodipine -- pharmacology
- Analgesics, Opioid -- pharmacology
- Animals
- Calcium Channel Blockers -- pharmacology
- Calcium Channels, L-Type -- drug effects
- Calcium Channels, T-Type -- drug effects
- Drug Synergism
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- pharmacology
- Enkephalin, D-Penicillamine (2,5)- -- pharmacology
- Male
- Mibefradil -- pharmacology
- Mice
- Morphine -- pharmacology
- Pain Measurement -- drug effects
- Postural Balance -- drug effects
- Receptors, Opioid, delta -- agonists
- Receptors, Opioid, kappa -- agonists
- Receptors, Opioid, mu -- agonists
- Spinal Cord -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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