Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. [electronic resource]
Producer: 20010521Description: 5025-30 p. digitalISSN:- 0027-8424
- Animals
- Animals, Newborn
- Calcium -- pharmacology
- Carcinoma, Squamous Cell -- genetics
- Cell Cycle
- Cell Differentiation -- drug effects
- Cell Size -- drug effects
- Cell Transformation, Neoplastic
- Cells, Cultured
- Cyclin-Dependent Kinase Inhibitor p16 -- metabolism
- DNA -- biosynthesis
- Gene Deletion
- Keratinocytes -- cytology
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Nuclear Matrix -- metabolism
- Nuclear Proteins
- Oncogene Protein p21(ras) -- metabolism
- Protein Transport
- Proteins -- genetics
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-mdm2
- Signal Transduction
- Tumor Suppressor Protein p14ARF
- Tumor Suppressor Protein p53 -- deficiency
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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