The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors. [electronic resource]
Producer: 20010426Description: 106-11 p. digitalISSN:- 0014-5793
- Amino Acid Sequence
- Animals
- Binding Sites
- GRB10 Adaptor Protein
- Humans
- In Vitro Techniques
- Phosphorylation
- Protein Structure, Tertiary
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Proteins -- chemistry
- Rats
- Receptor, IGF Type 1 -- antagonists & inhibitors
- Receptor, Insulin -- antagonists & inhibitors
- Recombinant Proteins -- metabolism
- Signal Transduction
- Substrate Specificity
- src Homology Domains
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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