Human hepatic metabolism of a novel 2-carboxyindole glycine antagonist for stroke: in vitro-in vivo correlations. [electronic resource]
Producer: 20010215Description: 843-56 p. digitalISSN:- 0049-8254
- Adult
- Aged
- Chromatography, High Pressure Liquid
- Cytochrome P-450 Enzyme System -- metabolism
- Female
- Glucuronides -- blood
- Glycine -- antagonists & inhibitors
- Humans
- Hydroxylation
- Indoles -- metabolism
- Kinetics
- Liver -- metabolism
- Male
- Mass Spectrometry
- Metabolic Clearance Rate
- Microsomes, Liver -- enzymology
- Middle Aged
- Mixed Function Oxygenases -- metabolism
- Stroke -- drug therapy
- Sulfates -- blood
- Time Factors
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Publication Type: Journal Article
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