Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells. [electronic resource]
Producer: 20001013Description: 5196-203 p. digitalISSN:- 0008-5472
- Aniline Compounds -- metabolism
- Antineoplastic Agents -- metabolism
- Aryl Hydrocarbon Hydroxylases
- Benzoflavones -- pharmacology
- Benzothiazoles
- Breast Neoplasms -- drug therapy
- Cytochrome P-450 CYP1A1 -- antagonists & inhibitors
- Cytochrome P-450 CYP1B1
- Cytochrome P-450 Enzyme System -- metabolism
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Humans
- Hydroxylation
- Isoenzymes -- antagonists & inhibitors
- Mixed Function Oxygenases -- biosynthesis
- Protein Binding
- Substrate Specificity
- Thiazoles -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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