Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. [electronic resource]
Producer: 20000928Description: 4881-8 p. digitalISSN:- 0008-5472
- Abnormalities, Multiple -- genetics
- Ataxia Telangiectasia -- genetics
- Cell Cycle -- physiology
- Cell Line
- Cell Survival -- radiation effects
- Checkpoint Kinase 2
- Chromosome Breakage
- Chromosomes, Human -- radiation effects
- DNA -- radiation effects
- DNA Damage
- DNA Repair
- Fibroblasts -- pathology
- Humans
- Interphase -- genetics
- Mitosis -- genetics
- Phosphorylation
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases
- Radiation Tolerance -- genetics
- Syndrome
- Tumor Suppressor Protein p53 -- biosynthesis
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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