Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. [electronic resource]
Producer: 20001229Description: 36152-7 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Bacterial Proteins -- antagonists & inhibitors
- Carrier Proteins -- chemistry
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Differentiation
- Cytosol -- chemistry
- Enzyme Activation
- Humans
- Inhibitor of Apoptosis Proteins
- Insect Proteins
- Intracellular Signaling Peptides and Proteins
- Membrane Glycoproteins -- metabolism
- Mitochondria -- metabolism
- Mitochondrial Proteins
- Molecular Sequence Data
- Mutation -- genetics
- Protein Binding
- Protein Isoforms -- chemistry
- Proteins -- chemistry
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Receptors, Tumor Necrosis Factor -- metabolism
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand
- Transfection
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- metabolism
- X-Linked Inhibitor of Apoptosis Protein
- bcl-X Protein
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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