Diminished natriuretic response to dopamine in old rats is due to an impaired D1-like receptor-signaling pathway. [electronic resource]
Producer: 20000907Description: 712-20 p. digitalISSN:- 0085-2538
- 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine -- pharmacology
- Adenylyl Cyclases -- metabolism
- Age Factors
- Aging -- physiology
- Animals
- Cardiotonic Agents -- pharmacology
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Dopamine -- pharmacology
- Dopamine Agonists -- pharmacology
- GTP-Binding Proteins -- metabolism
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Homeostasis -- physiology
- Kidney Tubules, Proximal -- enzymology
- Male
- Natriuresis -- drug effects
- Radioligand Assay
- Rats
- Rats, Inbred F344
- Receptors, Dopamine D1 -- physiology
- Signal Transduction -- drug effects
- Sodium -- metabolism
- Sodium-Hydrogen Exchangers -- analysis
- Sulfur Radioisotopes
- Tritium
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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