Interleukin-12 amplifies the M. leprae hsp65-cytotoxic response in the presence of tumour necrosis factor-alpha and interferon-gamma generating CD56+ effector cells: interleukin-4 downregulates this effect. [electronic resource]
Producer: 20000404Description: 262-70 p. digitalISSN:- 0300-9475
- Adult
- Aged
- Bacterial Proteins
- CD56 Antigen -- biosynthesis
- Cells, Cultured
- Chaperonin 60
- Chaperonins -- immunology
- Cytotoxicity, Immunologic -- immunology
- Down-Regulation -- immunology
- Drug Synergism
- Female
- Humans
- Immune Sera -- pharmacology
- Interferon-gamma -- antagonists & inhibitors
- Interleukin-10 -- physiology
- Interleukin-12 -- immunology
- Interleukin-4 -- physiology
- Interphase -- immunology
- Leprosy -- immunology
- Leukocytes, Mononuclear -- immunology
- Lymphocyte Activation -- immunology
- Major Histocompatibility Complex -- immunology
- Male
- Middle Aged
- Mycobacterium leprae -- immunology
- Protein Binding -- immunology
- T-Lymphocytes, Cytotoxic -- immunology
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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