Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes. [electronic resource]
Producer: 20000207Description: 360-6 p. digitalISSN:- 0194-911X
- Albuminuria -- chemically induced
- Angiotensin II -- adverse effects
- Angiotensinogen -- genetics
- Animals
- Animals, Genetically Modified
- Blood Pressure
- Cyclosporine -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Heart Diseases -- chemically induced
- Humans
- Hypertension, Renal -- chemically induced
- Interleukin-6 -- genetics
- Kidney -- cytology
- Male
- Monocytes -- cytology
- Myocardium -- cytology
- NF-kappa B -- metabolism
- Neutrophils -- cytology
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase -- genetics
- Nitric Oxide Synthase Type II
- Protein Binding -- drug effects
- Rats
- Renin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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