Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal re-organization and mitogenesis. [electronic resource]
Producer: 20000224Description: 2103-14 p. digitalISSN:- 0021-9258
- Activating Transcription Factor 2
- Animals
- CCAAT-Enhancer-Binding Proteins
- CHO Cells
- Cell Division -- drug effects
- Cricetinae
- Cyclic AMP Response Element-Binding Protein -- metabolism
- Cytoskeleton -- enzymology
- DNA-Binding Proteins -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Human Growth Hormone -- pharmacology
- Humans
- Janus Kinase 2
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- genetics
- Phosphorylation
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins -- metabolism
- Rats
- Time Factors
- Transcription Factor CHOP
- Transcription Factors -- metabolism
- Transcription, Genetic
- Transcriptional Activation
- Transfection
- ets-Domain Protein Elk-1
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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