Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay-xenopus (FETAX): biotransformation and detoxification. [electronic resource]
Producer: 20000209Description: 35-47 p. digitalISSN:- 0270-3211
- Amitrole -- pharmacology
- Animals
- Benzoflavones -- pharmacology
- Biotransformation
- Cyclohexanes -- pharmacology
- Cyclohexenes
- Cytochrome P-450 Enzyme System -- metabolism
- Embryo, Nonmammalian -- drug effects
- Embryonic Development
- Enzyme Inhibitors -- pharmacology
- Extremities -- embryology
- Male
- Microsomes, Liver -- drug effects
- No-Observed-Adverse-Effect Level
- Rats
- Rats, Sprague-Dawley
- Teratogens -- metabolism
- Thalidomide -- metabolism
- Toxicity Tests -- methods
- Xenopus laevis -- embryology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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