Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development. [electronic resource]
Producer: 19990805Description: 303-10 p. digitalISSN:- 0006-2952
- Antineoplastic Agents -- pharmacology
- Aziridines -- pharmacology
- Cell Survival -- drug effects
- Cytochrome Reductases -- antagonists & inhibitors
- Cytochrome-B(5) Reductase
- Enzyme Inhibitors -- pharmacology
- Flavonoids -- pharmacology
- Humans
- Indolequinones
- Indoles -- pharmacology
- NAD(P)H Dehydrogenase (Quinone) -- antagonists & inhibitors
- NADPH-Ferrihemoprotein Reductase -- antagonists & inhibitors
- Tirapazamine
- Triazines -- pharmacology
- Tumor Cells, Cultured
- Vitamin K -- pharmacology
- Xanthenes -- pharmacology
- Xanthones
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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