DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III. [electronic resource]
Producer: 19990819Description: 21679-87 p. digitalISSN:- 0021-9258
- Adenosine Monophosphate -- metabolism
- Adenosine Triphosphate -- metabolism
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Binding Sites
- Catalytic Domain
- Conserved Sequence
- DNA Footprinting
- DNA Ligase ATP
- DNA Ligases -- chemistry
- DNA Repair
- Deoxyribonuclease I
- Humans
- Lysine
- Mammals
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Poly(ADP-ribose) Polymerases -- chemistry
- Poly-ADP-Ribose Binding Proteins
- Recombinant Proteins -- chemistry
- Sequence Alignment
- Sequence Homology, Amino Acid
- Xenopus Proteins
- Zinc Fingers
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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